Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CCR1 | P32246 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779535 | 0.94 | MEN1 (0.80) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6776780 | 0.94 | RXFP1 (0.66) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6785761 | 0.93 | MEN1 (0.71) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6785309 | 0.93 | MEN1 (0.79) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6781774 | 0.90 | MEN1 (0.58) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6779215 | 0.87 | RXFP1 (0.58) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6781053 | 0.82 | MEN1 (0.79) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL13313585 | 0.82 | KDM4E (0.61) | MEN1KMT2ACCR1KDM4EALDH1A1 | |
| SCHEMBL6779616 | 0.81 | MEN1 (0.77) | MEN1KMT2AKDM4EALDH1A1PKM | |
| SCHEMBL6781607 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |