⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802371 | 1.00 | — | — | |
| SCHEMBL5000310 | 1.00 | — | — | |
| Cadaverine Tartrate SCHEMBL2841061 | 0.85 | — | — | |
| Ethylene SCHEMBL9699905 | 0.79 | — | — | |
| SCHEMBL1326512 | 0.78 | — | — | |
| SCHEMBL9252531 | 0.77 | — | — | |
| SCHEMBL9875875 | 0.75 | — | — | |
| SCHEMBL9257895 | 0.75 | — | — | |
| SCHEMBL8345431 | 0.74 | — | — | |
| SCHEMBL8866960 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080131511-A1 | Pharmaceutical Composition for Treatment of Tear and Salivary Fluid Drying | ASTELLAS PHARMA, INC. | 2008-06-05 | — | — | US | claimed |
| US-20070105934-A1 | Pharmaceutical composition for treatment of tear and salivary fluid drying | ASTELLAS PHARMA INC. (JP) | 2007-05-10 | — | — | US | claimed |
| EP-1712230-A1 | PHARMACEUTICAL COMPOSITION FOR XEROPHTHALMIA AND XEROSTOMIA TREATMENT | Astellas Pharma Inc. (JP) | 2006-10-18 | — | — | EP | claimed |
| EP-0590150-B1 | (-)-(S)-2,8-DIMETHYL-3-METHYLENE-1-OXA-8-AZASPIRO 4,5]DECANE L-TARTRATE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-07-08 | — | — | EP | claimed |
| EP-0311313-B1 | Heterocyclic spiro compounds and their preparation | YAMANOUCHI PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | claimed |
| US-5412096-A | Treatment of senile dementia, Alzheimer*s disease, cholinergic activators | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | claimed |
| EP-0397582-B1 | Imide groups containing polymers made from hindered diamines | CIBA GEIGY AG (CH) | 1994-12-14 | — | — | EP | claimed |
| US-RE34653-E | 1-oxa-8-azaspiro/4,5/decane compounds | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-07-05 | — | — | US | claimed |
| EP-0590150-A1 | (-)-(S)-2,8-DIMETHYL-3-METHYLENE-1-OXA-8-AZASPIRO 4,5]DECANE L-TARTRATE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-04-06 | — | — | EP | claimed |
| EP-0397582-A1 | Imide groups containing polymers made from hindered diamines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | claimed |
| US-4940795-A | Heterocyclic spiro compounds and methods for preparing the same | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | claimed |
| EP-0311313-A2 | Heterocyclic spiro compounds and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-04-12 | — | — | EP | claimed |
| US-20260147006-A1 | SCREENING METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-05-28 | — | — | US | disclosed |
| EP-4626868-A1 | 3-PHENYLQUINAZOLINONES AS NOVEL ANTI-CANCER THERAPY | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-10-08 | — | — | EP | disclosed |
| US-12298319-B2 | Method for measuring alpha value of muscarinic M1 receptor positive allosteric modulators | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-05-13 | — | — | US | disclosed |
| WO-2025070733-A1 | ANTI-RTK ANTIBODIES AND USES THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-04-03 | — | — | WO | disclosed |
| US-4996210-A | Cognition activators, nervous system disorders; muscarinic acetylcholine receptor agonists; 2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4.5]decane for example | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0397582-A1 | Imide groups containing polymers made from hindered diamines | CIBA-GEIGY AG (CH) | 1990-11-14 | — | — | EP | disclosed |
| US-4940795-A | Heterocyclic spiro compounds and methods for preparing the same | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0311313-A2 | Heterocyclic spiro compounds and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-04-12 | — | — | EP | disclosed |