SCHEMBL678193

SCHEMBL678193

COCCN=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15228548 0.85 NAAA (0.50)
SCHEMBL16709223 0.85 NAAA (0.50)
SCHEMBL841893 0.84
SCHEMBL16908373 0.82
SCHEMBL13207710 0.80
SCHEMBL16908363 0.77 MIF (0.40)
SCHEMBL330829 0.77 NAAA (0.55)
SCHEMBL18905772 0.75 MIF (0.35)
SCHEMBL18912064 0.75 PIK3CD (0.41)
SCHEMBL29410061 0.74 NAAA (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333424-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2025-10-30 US disclosed
EP-4563729-A1 AQUEOUS COMPOSITION FOR DEPOSITING A TIN SILVER ALLOY AND METHOD FOR ELECTROLYTI-CALLY DEPOSITING SUCH AN ALLOY Atotech Deutschland GmbH & Co. KG (DE) 2025-06-04 EP disclosed
US-20250034167-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2025-01-30 US disclosed
EP-3541804-B1 CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2025-01-22 EP disclosed
EP-3541802-B1 ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR AMGEN INC (US) 2025-01-01 EP disclosed
US-20230100838-A1 COVALENT RAS INHIBITORS AND USES THEREOF WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2023-03-30 US disclosed
WO-2022271658-A1 TRICYCLIC KRAS INHIBITORS ERASCA, INC. (US) 2022-12-29 WO disclosed
EP-4065231-A1 COVALENT RAS INHIBITORS AND USES THEREOF Revolution Medicines, Inc. (US) 2022-10-05 EP disclosed
CN-114980976-A Covalent RAS inhibitors and uses thereof 锐新医药公司 2022-08-30 CN disclosed
US-11191762-B2 Alkyl substituted triazole compounds as agonists of the APJ Receptor AMGEN INC. (US) 2021-12-07 US disclosed
US-4351896-A Mesoionic silver halide stabilizer precursor and use in a heat developable and heat stabilizable photographic silver halide material and process EASTMAN KODAK COMPANY (US) 1982-09-28 US disclosed
EP-0060094-A2 Guanidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-09-15 EP disclosed
EP-0054415-A1 Photographic material containing a mesoionic 1,2,4-triazolium-3-thiolate silver halide stabilizing and fixing agent EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-06-23 EP disclosed
EP-0054414-A1 Photographic material containing a silver halide stabilizer precursor compound EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-06-23 EP disclosed
EP-0045155-A1 Guanidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-02-03 EP disclosed
US-4279819-A GASTROINTESTINAL DISORDERS ALLEN & HANBURYS LTD. (GB) 1981-07-21 US disclosed
US-4255440-A ANTIALLERGENS, ANTIULCER AGENTS ALLEN & HANBURYS LIMITED (GB) 1981-03-10 US disclosed
US-4169855-A ANTIHISTAMINES, ANTISECRETORY AGENTS Allen & Hansbury, Limited (GB) 1979-10-02 US disclosed
US-4128658-A HISTAMINE ANTAGONISTS ALLEN & HANBURYS LIMITED (GB) 1978-12-05 US disclosed
US-4089887-A Process for the production of isothiocyanates DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1978-05-16 US disclosed