SCHEMBL6781966

SCHEMBL6781966

COC(=O)C(CCSC)NC(=O)c1ccc(NC(=O)c2cccnc2)cc1-c1ccccc1C

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 12/20 0.59
FNTB P49356 12/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6781970 1.00 FNTA (0.59) FNTAFNTB
SCHEMBL6777253 0.92 FNTA (0.71) FNTAFNTB
SCHEMBL6777248 0.92 FNTA (0.71) FNTAFNTB
SCHEMBL6775824 0.91 FNTA (0.61) FNTAFNTB
SCHEMBL6775820 0.91 FNTA (0.61) FNTAFNTB
SCHEMBL6775716 0.86 FNTA (0.65) FNTAFNTB
SCHEMBL6775714 0.86 FNTA (0.65) FNTAFNTB
SCHEMBL7145915 0.84 FNTA (0.58) FNTAFNTB
SCHEMBL7609412 0.83 FNTA (0.59) FNTAFNTB
SCHEMBL7609414 0.83 FNTA (0.59) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6693123-B2 (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA UNIVERSITY OF PITTSBURGH 2004-02-17 US disclosed
EP-0873123-B1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIV PITTSBURGH (US) 2003-04-09 EP disclosed