Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.58 |
| ▸ | FNTB | P49356 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775824 | 0.93 | FNTA (0.61) | FNTAFNTBTDP1KMT2APGGT1B | |
| SCHEMBL7134723 | 0.93 | FNTA (0.56) | FNTAFNTBTDP1PGGT1B | |
| SCHEMBL7134716 | 0.93 | FNTA (0.56) | FNTAFNTBTDP1PGGT1B | |
| SCHEMBL6775820 | 0.93 | FNTA (0.61) | FNTAFNTBTDP1KMT2APGGT1B | |
| SCHEMBL7609412 | 0.85 | FNTA (0.59) | FNTAFNTBTDP1PGGT1B | |
| SCHEMBL7609414 | 0.85 | FNTA (0.59) | FNTAFNTBTDP1PGGT1B | |
| Hydrochloric Acid SCHEMBL6781385 | 0.84 | FNTA (0.58) | FNTAFNTBTDP1PGGT1B | |
| Hydrochloric Acid SCHEMBL6775831 | 0.84 | FNTA (0.58) | FNTAFNTBTDP1PGGT1B | |
| Hydrochloric Acid SCHEMBL6775840 | 0.84 | FNTA (0.58) | FNTAFNTBTDP1PGGT1B | |
| SCHEMBL6781966 | 0.84 | FNTA (0.59) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873123-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0873123-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0873123-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017070-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-05-15 | — | — | WO | disclosed |