Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876379 | 0.88 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6887529 | 0.86 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL20084555 | 0.85 | CA1 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8863056 | 0.83 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL30859041 | 0.83 | CA1 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1907531 | 0.83 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4616498 | 0.82 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| Hydrochloric Acid SCHEMBL11261755 | 0.82 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1894781 | 0.82 | CA1 (0.62) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11438493 | 0.82 | ALDH1A1 (0.48) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420484-B | Method for preparing amide compounds | 四川大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118420484-A | Method for preparing amide compounds | 四川大学 | 2024-08-02 | — | — | CN | claimed |
| CN-114369082-B | Pyridine substituted spiro compounds and application thereof in preparation of anti-plant virus agent | 贵州大学 | 2023-09-05 | — | — | CN | claimed |
| CN-114369082-A | Pyridine substituted spiro compound, preparation method thereof and application thereof in preparation of anti-plant virus medicament | 贵州大学 | 2022-04-19 | — | — | CN | claimed |
| CN-109336795-B | Preparation method of 3-trifluoromethylthiophenol and 3-methylthio benzotrifluoride | 利尔化学股份有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-109336795-A | The preparation method of 3- trifluoromethyl thiophenol and 3- methyl mercapto benzotrifluoride | 利尔化学股份有限公司 | 2019-02-15 | — | — | CN | claimed |
| WO-2013102936-A1 | N-(3-((DIETHYLAMINO) METHYL)-4-HYDROXYPHENYL)-N-(QUINOLIN-4-YL) SULFONAMIDES FOR THE TREATMENT OF TUBERCULOSIS AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-07-11 | — | — | WO | claimed |
| CN-102531978-A | Preparation method of thiophenol | UNIV ZHEJIANG | 2012-07-04 | — | — | CN | claimed |
| EP-2385831-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | The UAB Research Foundation (US) | 2011-11-16 | — | — | EP | claimed |
| US-20110254866-A1 | INFORMATION PROCESSING APPARATUS, METHOD AND PROGRAM THEREFORE | SONY CORPORATION (JP) | 2011-10-20 | — | — | US | claimed |
| WO-2010123591-A2 | SMALL MOLECULE INHIBITORS OF NADS, NAMNAT, AND NMNAT | THE UAB RESEARCH FOUNDATION (US) | 2010-10-28 | — | — | WO | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-0193390-B1 | AN N-(2-CHLORO-4-TRIFLUOROMETHYLPHENYL)-3-TRIFLUOROMETHYL-BENZENESULFONAMIDE DERIVATIVE, PROCESS OF PREPARING IT AND AGRICULTURAL FUNGICIDE CONTAINING IT | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-05-04 | — | — | EP | claimed |
| EP-0193390-A1 | An n-(2-chloro-4-trifluoromethylphenyl)-3-trifluoromethyl-benzenesulfonamide derivative, process of preparing it and agricultural fungicide containing it | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-09-03 | — | — | EP | claimed |
| EP-0021592-A1 | Phenylsulphonamide derivatives, a process for their preparation and their use as medicines | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1981-01-07 | — | — | EP | claimed |
| JP-63104952-A | — | — | None | — | — | JP | disclosed |
| JP-63270658-A | — | — | None | — | — | JP | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4049695-A | BACTERICIDE, FUNGICIDE | THE DOW CHEMICAL COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |