Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778614 | 0.87 | MAPT (0.61) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL9627341 | 0.83 | MAPT (0.45) | MAPTPOLBSMN1; SMN2PTGS2CHRNB2 | |
| SCHEMBL9628616 | 0.83 | MAPT (0.47) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL8046959 | 0.81 | MAPT (0.45) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL8046962 | 0.81 | MAPT (0.45) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL13784551 | 0.80 | MAPT (0.60) | MAPTPOLBSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6778438 | 0.80 | GAA (0.62) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL12394853 | 0.79 | MAPT (0.49) | MAPTPOLBSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6780646 | 0.79 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1TSHRCHRNB2 | |
| SCHEMBL6774718 | 0.79 | PTGS2 (0.65) | MAPTPOLBSMN1; SMN2ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770780-B1 | QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS | JSR CORPORATION (JP) | 2004-08-03 | — | — | US | disclosed |
| EP-1231205-A1 | VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS | JSR Corporation (JP) | 2002-08-14 | — | — | EP | disclosed |