SCHEMBL6783609

SCHEMBL6783609

CCCCC(=O)Oc1cccc(Br)c1F

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
KDM4E B2RXH2 1/20 0.55
RECQL P46063 1/20 0.55
POLM Q9NP87 2/20 0.47
POLK Q9UBT6 2/20 0.47
POLL Q9UGP5 2/20 0.47
POLH Q9Y253 2/20 0.47
ALOX15 P16050 1/20 0.41
HTR7 P34969 1/20 0.41
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
HTR2A P28223 1/20 0.39
PPARG P37231 2/20 0.37
PPARA Q07869 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
OGG1 O15527 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996651 0.85 KDM4E (0.57) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL5965055 0.84 ACHE (0.40) KMT2AMEN1KDM4ERECQLALOX15
SCHEMBL3254616 0.84 MEN1 (0.56) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL15558636 0.84 KMT2A (0.56) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL29010016 0.82 KDM4E (0.55) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL29009835 0.82 MEN1 (0.55) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL27632218 0.81 GRM4 (0.37) KMT2AMEN1KDM4ESMN1; SMN2
SCHEMBL8678126 0.81 POLM (0.54) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL8674993 0.80 MEN1 (0.59) KMT2AMEN1KDM4ERECQLPOLM
SCHEMBL28645467 0.80 KMT2A (0.50) KMT2AMEN1KDM4ERECQLPOLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6833458-B2 Selective serotonin reuptake inhibitor; antidepressant, anti-Parkinson agent DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) 2004-12-21 US claimed
CN-116209433-B Small molecule albumin binding agents 俄勒冈健康科学大学 2025-05-23 CN disclosed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed