Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922332 | 0.85 | MAPK1 (0.35) | LTA4HSMN1; SMN2ALDH1A1LMNATAAR1 | |
| SCHEMBL26383972 | 0.77 | LTA4H (0.46) | LTA4HSIGMAR1IDO1HRH3SMN1; SMN2 | |
| SCHEMBL4805626 | 0.74 | CA12 (0.41) | IDO1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25986524 | 0.71 | LTA4H (0.81) | LTA4HIDO1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL1425001 | 0.71 | LTA4H (0.81) | LTA4HIDO1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL27884 | 0.71 | LTA4H (0.81) | LTA4HIDO1SMN1; SMN2ALDH1A1CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL20919857 | 0.69 | LTA4H (0.77) | LTA4HIDO1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL2562583 | 0.69 | LTA4H (0.57) | LTA4HSIGMAR1IDO1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20636307 | 0.68 | LTA4H (0.47) | LTA4HSIGMAR1IDO1HRH3SMN1; SMN2 | |
| SCHEMBL21994566 | 0.66 | LTA4H (0.59) | LTA4HSIGMAR1IDO1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |