Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.60 |
| ▸ | USP2 | O75604 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585491 | 0.86 | HTT (0.51) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL4178072 | 0.86 | PRKDC (0.52) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL1734528 | 0.85 | PRKDC (0.53) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL2918443 | 0.82 | HTT (0.70) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL2797008 | 0.82 | HTT (1.00) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL2922462 | 0.82 | HTT (0.70) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL2923518 | 0.82 | HTT (0.70) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL2923310 | 0.82 | HTT (0.61) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| Hydrochloric Acid SCHEMBL2796907 | 0.81 | HTT (0.97) | HTTCYP1A2CYP3A4CLK4CYP2C19 | |
| SCHEMBL22631347 | 0.80 | HTT (0.63) | HTTCYP1A2CYP3A4CLK4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169795-C | Nitrogenous heterocyclic compounds | Э�ͷ���ҵ��ʽ���� | 2004-10-06 | — | — | CN | disclosed |
| US-6750218-B2 | INHIBITORY ACTIVITY ON PHOSPHORYLATION OF PLATELET-DERIVED GROWTH FACTOR (PDGF) RECEPTOR USEFUL FOR THE TREATMENT OF CELL-PROLIFERATIVE DISEASES SUCH AS ARTERIOSCLEROSIS, VASCULAR REOBSTRUCTION, CANCER AND GLOMERULOSCLEROSIS | MILLENNIUMIUM PHARMACEUTICALS, INC. | 2004-06-15 | — | — | US | disclosed |
| CN-1208404-A | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1999-02-17 | — | — | CN | disclosed |