SCHEMBL6785778

SCHEMBL6785778

N#Cc1ccnc([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 13/20 0.48
PYGL P06737 3/20 0.41
SLC29A1 Q99808 1/20 0.40
SLC5A1 P13866 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6785773 1.00 SLC5A2 (0.48) SLC5A2PYGLSLC29A1SLC5A1
SCHEMBL6791154 0.80 SLC5A2 (0.49) SLC5A2PYGLSLC29A1SLC5A1
SCHEMBL6790264 0.80 SLC5A2 (0.49) SLC5A2PYGLSLC29A1SLC5A1
SCHEMBL6931690 0.80 SLC5A2 (0.49) SLC5A2PYGLSLC29A1SLC5A1
SCHEMBL6788997 0.79 SLC5A2 (0.47) SLC5A2PYGL
SCHEMBL6788460 0.79 SLC5A2 (0.47) SLC5A2PYGL
SCHEMBL6789429 0.79 SLC5A2 (0.45) SLC5A2PYGLSLC5A1
SCHEMBL6789918 0.79 SLC5A2 (0.46) SLC5A2PYGL
SCHEMBL6789913 0.79 SLC5A2 (0.46) SLC5A2PYGL
SCHEMBL6796002 0.79 SLC5A2 (0.45) SLC5A2PYGLSLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040266723-A1 Antiviral agents for treatment of Flaviviridae infections PHARMASSET, INC. 2004-12-30 US disclosed
CN-1527836-A Antiviral agents for treatment of flaviviridae infections 2004-09-08 CN disclosed
EP-1366055-A2 ANTIVIRAL AGENTS FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS Pharmasset Limited (BB) 2003-12-03 EP disclosed
WO-2002048165-A2 ANTIVIRAL AGENTS FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS PHARMASSET LTD. (BB) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266723-A1 Antiviral agents for treatment of Flaviviridae infections HAVCR2, MAVS, EIF2AK2 SLC5A2 309/4885PYGL 81/4885SLC29A1 19/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.