⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842442 | 1.00 | — | — | |
| Ethylene SCHEMBL2081704 | 0.73 | HSD17B10 (0.43) | — | |
| SCHEMBL2971600 | 0.73 | — | — | |
| SCHEMBL6202105 | 0.72 | — | — | |
| SCHEMBL7033066 | 0.72 | — | — | |
| SCHEMBL6561371 | 0.70 | — | — | |
| SCHEMBL7297953 | 0.69 | GSK3A (0.38) | — | |
| SCHEMBL1411619 | 0.66 | — | — | |
| SCHEMBL12490004 | 0.66 | — | — | |
| SCHEMBL8071530 | 0.65 | HSD17B10 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053823-B1 | OPTICALLY PURE BICYCLO (2.2.2) OCT-5-EN-2-ONES, PROCESS FOR THEIR PREPARATION AND THEIR UTILISATION | Studiengesellschaft Kohle mbH (DE) | 1985-04-10 | — | — | EP | claimed |
| US-4461687-A | Processes for the preparation of pure enantiomers of bicyclo(2,2,2)oct-5-en-2-ones | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1984-07-24 | — | — | US | claimed |
| US-4415756-A | Pure enantiomers of bicyclo[2.2.2]oct-5-en-2-ones, processes for their production and their use | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1983-11-15 | — | — | US | claimed |
| EP-0053823-A1 | Optically pure bicyclo (2.2.2) oct-5-en-2-ones, process for their preparation and their utilisation | Studiengesellschaft Kohle mbH (DE) | 1982-06-16 | — | — | EP | claimed |
| JP-3072442-A | — | — | None | — | — | JP | disclosed |
| JP-3072443-A | — | — | None | — | — | JP | disclosed |
| EP-4296365-B1 | PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID | VISOLIS INC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-4296365-A2 | PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID | Visolis, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3224368-B1 | PROCESSES FOR CONVERSION OF BIOLOGICALLY DERIVED MEVALONIC ACID | VISOLIS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-112279744-B | Method for the conversion of biologically derived mevalonate | 维索利斯有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-11492339-B2 | Processes for conversion of biologically derived mevalonic acid | Visolis, Inc. (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220145161-A1 | GREEN COMPOSITIONS FOR USE IN DOWNHOLE AND INDUSTRIAL APPLICATIONS | DELTA-ENERGY GROUP, LLC (US) | 2022-05-12 | — | — | US | disclosed |
| EP-0053823-A1 | Optically pure bicyclo (2.2.2) oct-5-en-2-ones, process for their preparation and their utilisation | Studiengesellschaft Kohle mbH (DE) | 1982-06-16 | — | — | EP | disclosed |
| EP-0046488-A2 | Substituted 2,5,7-trioxa-bicyclo(2.2.2)octan-6-ones, 3,6,8-trioxa-bicyclo(3.2.1)octan-4-ones and 1,3-dioxane-carboxylic acid and 1,3-dioxolane-2-carboxylic acid compounds, and their preparation | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-03-03 | — | — | EP | disclosed |
| US-4167947-A | Substituted bicyclooctenemethanols, process for producing same and uses of same for augmenting or enhancing the organoleptic properties of smoking compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-09-18 | — | — | US | disclosed |
| US-4166916-A | ENHANCES ORGANOLEPTIC PROPERTIES OF TOBACCOS AND PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-09-04 | — | — | US | disclosed |
| US-4163737-A | Substituted bicyclooctenemethanols, process for producing same and uses of same for augmenting or enhancing the organoleptic properties of tobaccos, perfumes and perfumed articles | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4139484-A | SOAPS, PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4128729-A | ORGANOLEPTIC | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-3967629-A | Bicyclic fragrance materials and processes therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-07-06 | — | — | US | disclosed |