Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678634 | 0.69 | — | — | |
| SCHEMBL2842442 | 0.69 | — | — | |
| Benzoquinone SCHEMBL984234 | 0.65 | MAOA (0.42) | — | |
| SCHEMBL6561371 | 0.63 | — | — | |
| SCHEMBL11179705 | 0.63 | — | — | |
| SCHEMBL3276103 | 0.63 | — | — | |
| SCHEMBL137542 | 0.63 | — | — | |
| Maleic Anhydride SCHEMBL219660 | 0.62 | — | — | |
| SCHEMBL13508673 | 0.61 | — | — | |
| SCHEMBL3898157 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455195-B1 | Ethanobicyclic amine derivatives for CNS disorders | SEARLE & CO (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5215992-A | Treating psychotic, convulsive, dystonic disorders, cerebral ischemia | G. D. SEARLE & CO. (US) | 1993-06-01 | — | — | US | disclosed |
| US-5089506-A | Antipsychotic agents, anticonvulsants | G. D. SEARLE & CO. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0455195-A2 | Ethanobicyclic amine derivatives for CNS disorders | G.D. Searle & Co. (US) | 1991-11-06 | — | — | EP | disclosed |