Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442007 | 0.77 | MAPK1 (0.45) | HSD17B10TSHRMAPK1GAAPTPN1 | |
| SCHEMBL10546978 | 0.77 | PTPN1 (0.47) | HSD17B10TSHRMAPK1GAAPTPN1 | |
| SCHEMBL10680843 | 0.74 | KDM4E (0.40) | HSD17B10MAPK1GAAKDM4EALDH1A1 | |
| SCHEMBL151820 | 0.73 | HSD17B10 (0.57) | HSD17B10TSHRGAANPSR1KDM4E | |
| SCHEMBL318039 | 0.73 | TSHR (0.49) | TSHRMAPK1GAAPTPN1KDM4E | |
| SCHEMBL30969123 | 0.73 | HSD17B10 (0.57) | HSD17B10TSHRGAANPSR1KDM4E | |
| SCHEMBL31042841 | 0.72 | HSD17B10 (0.53) | HSD17B10TSHRGAANPSR1KDM4E | |
| SCHEMBL9876858 | 0.72 | MAPK1 (0.58) | HSD17B10TSHRMAPK1GAAPTPN1 | |
| SCHEMBL6068431 | 0.72 | TNFSF11 (0.50) | HSD17B10TSHRGAANPSR1KDM4E | |
| SCHEMBL151821 | 0.71 | TSHR (0.55) | TSHRMAPK1GAAPTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040230064-A1 | Novel labeled resiniferatoxin derivatives | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-18 | — | — | US | disclosed |
| EP-1341795-A2 | NOVEL LABELED RESINIFERATOXIN DERIVATIVES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002030937-A2 | LABELED RESINIFERATOXIN DERIVATIVES FOR USE IN VANILLOID RECEPTOR BINDING ASSAY | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230064-A1 | Novel labeled resiniferatoxin derivatives | TRPV1, GPR17, ANTXR2 | HSD17B10 1438/4885TSHR 1783/4885MAPK1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.