Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546978 | 0.84 | PTPN1 (0.47) | MAPK1CFDHSD17B10PTPN1KDM4E | |
| SCHEMBL10442008 | 0.81 | MAPK1 (0.50) | MAPK1CFDHSD17B10PTPN1KDM4E | |
| SCHEMBL9876858 | 0.79 | MAPK1 (0.58) | MAPK1HSD17B10PTPN1KDM4ETSHR | |
| SCHEMBL149945 | 0.79 | HSD17B10 (0.53) | HSD17B10PTPN1KDM4ETSHRALDH1A1 | |
| SCHEMBL10441976 | 0.79 | CRHBP (0.40) | MAPK1CFDHSD17B10PTPN1KDM4E | |
| SCHEMBL6786368 | 0.77 | HSD17B10 (0.44) | MAPK1CFDHSD17B10PTPN1KDM4E | |
| SCHEMBL21617915 | 0.76 | ABCB11 (0.42) | MAPK1HSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL27517149 | 0.74 | TDP1 (0.49) | MAPK1HSD17B10PTPN1KDM4ETSHR | |
| SCHEMBL2381169 | 0.73 | CXCL8 (0.56) | MAPK1HSD17B10KDM4ETSHRALDH1A1 | |
| SCHEMBL24541754 | 0.72 | HSD17B10 (0.53) | MAPK1HSD17B10KDM4ETSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |