Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK8 | O60259 | 1/20 | 0.41 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.41 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 4/20 | 0.39 |
| ▸ | PLAU | P00749 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6786589 | 0.99 | KLK8 (0.40) | KLK8KLK6KLK14KLK5PLG | |
| SCHEMBL6783458 | 0.95 | KLK8 (0.42) | KLK8KLK6KLK14KLK5PLG | |
| Hydrochloric Acid SCHEMBL6783450 | 0.94 | KLK8 (0.42) | KLK8KLK6KLK14KLK5PLG | |
| SCHEMBL6788443 | 0.91 | KLK8 (0.42) | KLK8KLK6KLK14KLK5PLG | |
| Hydrochloric Acid SCHEMBL6788432 | 0.90 | KLK8 (0.41) | KLK8KLK6KLK14KLK5PLG | |
| SCHEMBL6790534 | 0.89 | PLAU (0.44) | KLK8KLK6KLK14KLK5PLG | |
| SCHEMBL6782996 | 0.88 | KLK8 (0.43) | KLK8KLK6KLK14KLK5PLG | |
| Hydrochloric Acid SCHEMBL6790527 | 0.88 | PLAU (0.43) | KLK8KLK6KLK14KLK5PLG | |
| Hydrochloric Acid SCHEMBL6782992 | 0.88 | KLK8 (0.42) | KLK8KLK6KLK14KLK5PLG | |
| SCHEMBL6781492 | 0.87 | KLK6 (0.45) | KLK8KLK6KLK14KLK5PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699862-B1 | ANTITUMOR | PFIZER INC. | 2004-03-02 | — | — | US | claimed |