Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.44 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | KLK8 | O60259 | 1/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.40 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6790527 | 0.99 | PLAU (0.43) | PLAUPLGKLK8KLK6KLK14 | |
| SCHEMBL6783458 | 0.92 | KLK8 (0.42) | PLAUPLGKLK8KLK6KLK14 | |
| Hydrochloric Acid SCHEMBL6783450 | 0.91 | KLK8 (0.42) | PLAUPLGKLK8KLK6KLK14 | |
| SCHEMBL6787921 | 0.89 | KDM4E (0.46) | PLAUPLGKLK8KLK6KLK14 | |
| SCHEMBL6786597 | 0.89 | KLK8 (0.41) | PLAUPLGKLK8KLK6KLK14 | |
| Hydrochloric Acid SCHEMBL6786589 | 0.88 | KLK8 (0.40) | PLAUPLGKLK8KLK6KLK14 | |
| Hydrochloric Acid SCHEMBL6787915 | 0.88 | KDM4E (0.45) | PLAUPLGKLK8KLK6KLK14 | |
| SCHEMBL6781492 | 0.86 | KLK6 (0.45) | PLAUPLGKLK8KLK6KLK14 | |
| Hydrochloric Acid SCHEMBL6781488 | 0.85 | KLK6 (0.45) | PLAUPLGKLK8KLK6KLK14 | |
| SCHEMBL6782996 | 0.85 | KLK8 (0.43) | PLAUPLGKLK8KLK6KLK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699862-B1 | ANTITUMOR | PFIZER INC. | 2004-03-02 | — | — | US | claimed |