Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 4/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313786 | 0.86 | NPY1R (0.50) | MMEPOLBNPY1RNPY5RCTSB | |
| SCHEMBL5313792 | 0.86 | NPY1R (0.50) | MMEPOLBNPY1RNPY5RCTSB | |
| SCHEMBL9828894 | 0.85 | MME (0.63) | MMEPOLBACECPA1ACE2 | |
| SCHEMBL9828899 | 0.85 | MME (0.63) | MMEPOLBACECPA1ACE2 | |
| SCHEMBL7597310 | 0.85 | NPY1R (0.52) | MMEPOLBNPY1RNPY5RCNR1 | |
| SCHEMBL8121995 | 0.85 | NPY1R (0.52) | MMEPOLBNPY1RNPY5RCNR1 | |
| SCHEMBL7597314 | 0.85 | NPY1R (0.52) | MMEPOLBNPY1RNPY5RCNR1 | |
| SCHEMBL9825139 | 0.84 | MME (0.65) | MMEPOLBACECPA1ACE2 | |
| SCHEMBL9830037 | 0.84 | MME (0.62) | MMEPOLBACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL9200911 | 0.84 | NPY1R (0.51) | MMEPOLBNPY1RNPY5RCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825354-B2 | OSTEOPOROSIS; RHEUMATIC DISEASES | WYETH HOLDINGS CORPORATION | 2004-11-30 | — | — | US | disclosed |
| US-6340691-B1 | TREATMENT OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN CYANAMID COMPANY | 2002-01-22 | — | — | US | disclosed |