Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121995 | 1.00 | NPY1R (0.52) | NPY1RNPY5RCPB2MMECTSD | |
| SCHEMBL7597314 | 1.00 | NPY1R (0.52) | NPY1RNPY5RCPB2MMECTSD | |
| Hydrochloric Acid SCHEMBL9200911 | 0.98 | NPY1R (0.51) | NPY1RNPY5RCPB2MMECTSD | |
| SCHEMBL8118883 | 0.95 | CPB2 (0.55) | NPY1RNPY5RCPB2MMECTSD | |
| SCHEMBL9197461 | 0.95 | CPB2 (0.55) | NPY1RNPY5RCPB2MMECTSD | |
| SCHEMBL8118882 | 0.95 | CPB2 (0.55) | NPY1RNPY5RCPB2MMECTSD | |
| SCHEMBL8120862 | 0.90 | NPY1R (0.54) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL8526459 | 0.90 | NPY1R (0.54) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL9201260 | 0.87 | NPY1R (0.55) | NPY1RNPY5RCTSDNPY4RNPFFR1 | |
| SCHEMBL5313786 | 0.86 | NPY1R (0.50) | NPY1RNPY5RMMECTSDNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686183-B1 | L-ORNITHINE PHENYL ACETATE AND METHODS OF MAKING THEREOF | OCERA THERAPEUTICS INC (US) | 2022-08-03 | — | — | EP | disclosed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |