Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 13/20 | 0.46 |
| ▸ | GRM6 | O15303 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789091 | 1.00 | GRM2 (0.46) | GRM2GRM3GRM6LMNATP53 | |
| SCHEMBL6910384 | 1.00 | GRM2 (0.46) | GRM2GRM3GRM6LMNATP53 | |
| SCHEMBL6787505 | 0.85 | GRM2 (0.53) | GRM2GRM3GRM6 | |
| SCHEMBL6788902 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GAA | |
| SCHEMBL6908511 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GAA | |
| SCHEMBL6909715 | 0.85 | GRM2 (0.53) | GRM2GRM3GRM6 | |
| SCHEMBL6787502 | 0.85 | GRM2 (0.53) | GRM2GRM3GRM6 | |
| SCHEMBL6908514 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GAA | |
| SCHEMBL6794862 | 0.83 | GRM2 (0.52) | GRM2GRM3GRM6LMNA | |
| SCHEMBL6794702 | 0.82 | GRM2 (0.47) | GRM2GRM3GRM6GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |