Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 19/20 | 0.53 |
| ▸ | GRM3 | Q14832 | 19/20 | 0.53 |
| ▸ | GRM6 | O15303 | 9/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787505 | 1.00 | GRM2 (0.53) | GRM2GRM3GRM6GRM8 | |
| SCHEMBL6787502 | 1.00 | GRM2 (0.53) | GRM2GRM3GRM6GRM8 | |
| SCHEMBL6788902 | 0.87 | GRM2 (0.56) | GRM2GRM3GRM6 | |
| SCHEMBL6908514 | 0.87 | GRM2 (0.56) | GRM2GRM3GRM6 | |
| SCHEMBL6908511 | 0.87 | GRM2 (0.56) | GRM2GRM3GRM6 | |
| SCHEMBL6794862 | 0.85 | GRM2 (0.52) | GRM2GRM3GRM6GRM8 | |
| SCHEMBL6910384 | 0.85 | GRM2 (0.46) | GRM2GRM3GRM6 | |
| SCHEMBL6789091 | 0.85 | GRM2 (0.46) | GRM2GRM3GRM6 | |
| SCHEMBL6789089 | 0.85 | GRM2 (0.46) | GRM2GRM3GRM6 | |
| SCHEMBL6794011 | 0.82 | GRM2 (0.55) | GRM2GRM3GRM6GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |