Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6791894 | 0.91 | TAAR1 (0.73) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL6789489 | 0.83 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL6790627 | 0.82 | TAAR1 (0.58) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL6790294 | 0.81 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL2411151 | 0.80 | TAAR1 (0.58) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL6784490 | 0.80 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL8084560 | 0.80 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL3247948 | 0.78 | TAAR1 (0.56) | TAAR1SLC2A1MAPTTP53NPC1 | |
| SCHEMBL10144336 | 0.76 | TAAR1 (0.53) | TAAR1SLC2A1ALDH1A1MAPTTP53 | |
| SCHEMBL3244058 | 0.76 | TAAR1 (0.69) | TAAR1SLC2A1ALDH1A1TGM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | GALR3, GALR2, GALR1 | TAAR1 270/4885SLC2A1 1700/4885ALDH1A1 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.