Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784490 | 0.90 | TAAR1 (0.59) | TAAR1NPY5RSLC2A1ALDH1A1TGM2 | |
| SCHEMBL8084560 | 0.90 | TAAR1 (0.59) | TAAR1NPY5RSLC2A1ALDH1A1TGM2 | |
| SCHEMBL4415371 | 0.90 | APP (0.50) | TAAR1NPY5RSLC2A1POLA1MAPT | |
| SCHEMBL6791894 | 0.87 | TAAR1 (0.73) | TAAR1SLC2A1ALDH1A1TGM2MEN1 | |
| SCHEMBL6789185 | 0.82 | TAAR1 (0.62) | TAAR1SLC2A1ALDH1A1TGM2MEN1 | |
| SCHEMBL6789489 | 0.80 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MAPT | |
| SCHEMBL6790294 | 0.80 | TAAR1 (0.59) | TAAR1SLC2A1ALDH1A1TGM2MEN1 | |
| SCHEMBL10144336 | 0.79 | TAAR1 (0.53) | TAAR1SLC2A1ALDH1A1MEN1KMT2A | |
| SCHEMBL3244058 | 0.79 | TAAR1 (0.69) | TAAR1SLC2A1ALDH1A1TGM2MEN1 | |
| SCHEMBL3247948 | 0.77 | TAAR1 (0.56) | TAAR1SLC2A1MAPTNFKB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2140864-A2 | Use of GAL3 receptor antagonists for the treatment of depression and / or anxiety and compounds useful in such methods | H.Lundbeck A/S (DK) | 2010-01-06 | — | — | EP | disclosed |
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | GALR3, GALR2, GALR1 | TAAR1 270/4885NPY5R 123/4885SLC2A1 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.