⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293710 | 0.80 | — | — | |
| SCHEMBL6443242 | 0.74 | — | — | |
| SCHEMBL13074417 | 0.72 | AR (0.52) | — | |
| SCHEMBL65952 | 0.69 | — | — | |
| SCHEMBL5154501 | 0.68 | — | — | |
| SCHEMBL11392877 | 0.68 | — | — | |
| SCHEMBL1201107 | 0.67 | KDM4E (0.53) | — | |
| SCHEMBL8619374 | 0.66 | — | — | |
| SCHEMBL28896011 | 0.66 | HMBS (0.92) | — | |
| SCHEMBL27763219 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | claimed |
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |
| US-20240317705-A1 | POTASSIUM CHANNEL MODULATORS | NOVARTIS AG (CH) | 2024-09-26 | — | — | US | disclosed |
| US-20240285611-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC. (US) | 2024-08-29 | — | — | US | disclosed |
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2024-07-25 | — | — | US | disclosed |
| CN-118307623-A | Steroid compound, application thereof and pharmaceutical composition containing steroid compound | 北京华睿鼎信科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2023-12-05 | — | — | US | disclosed |
| US-11786519-B2 | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBVIE INC. (US) | 2023-10-17 | — | — | US | disclosed |
| EP-3700911-B1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2023-09-06 | — | — | EP | disclosed |
| US-20230265077-A1 | Photoactive Compound, Photoactive Protein-Immobilizing Gel And Use | Water Bear Health Technology (Nantong) Co., LTD. (CN) | 2023-08-24 | — | — | US | disclosed |
| WO-2011050160-A1 | PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| EP-1756095-B1 | CYANOPYRROLE CONTAINING CYCLIC CARBAMATE AND THIOCARBAMATE BIARYLS AND METHODS FOR PREPARING THE SAME | WYETH CORP (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20040077880-A1 | Sulfonylpyrroles | BAYER CROPSCIENCE AG (DE) | 2004-04-22 | — | — | US | disclosed |
| EP-1345934-A2 | SULFONYLPYRROLES | Bayer CropScience AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050069-A2 | SULFONYLPYRROLES FOR CONTROLLING MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2002-06-27 | — | — | WO | disclosed |
| CN-1077955-A | Hete rocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-11-03 | — | — | CN | disclosed |
| EP-0079623-B1 | PROCESS FOR THE PREPARATION OF 1H-PYRROLE-2-ACETIC ESTERS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4493935-A | SAPONIFICATION IH-PYRROL-2-ACETONITRILE (OR-ACETAMIDE), THEN 7AR-) | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-01-15 | — | — | US | disclosed |
| EP-0079623-A2 | Process for the preparation of 1H-pyrrole-2-acetic esters | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1983-05-25 | — | — | EP | disclosed |
| US-4006160-A | Process for the synthesis of N-hydroxypyrroles, N-hydroxyimidazoles, and derivatives thereof | UNIVERSITY OF ALABAMA (US) | 1977-02-01 | — | — | US | disclosed |