Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 1.00 |
| ▸ | GRM3 | Q14832 | 18/20 | 1.00 |
| ▸ | GRM6 | O15303 | 3/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 1/20 | 1.00 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709229 | 1.00 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL24606225 | 1.00 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6793703 | 0.87 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6906939 | 0.87 | GRM2 (0.83) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6906931 | 0.87 | GRM2 (0.83) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6795693 | 0.86 | GRM2 (0.78) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6794351 | 0.85 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6793748 | 0.84 | GRM2 (0.73) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6788367 | 0.84 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL7312412 | 0.84 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |