Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12522704 | 0.99 | P2RX4 (0.49) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL680548 | 0.88 | CYP19A1 (0.49) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL14219833 | 0.87 | CYP19A1 (0.47) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL10977145 | 0.87 | CYP19A1 (0.64) | P2RX4CYP19A1KMT2ASRCALDH1A1 | |
| SCHEMBL10977143 | 0.87 | CYP19A1 (0.64) | P2RX4CYP19A1KMT2ASRCALDH1A1 | |
| SCHEMBL28552714 | 0.84 | CYP19A1 (0.47) | P2RX4CYP19A1KMT2ASRCALDH1A1 | |
| SCHEMBL8687390 | 0.84 | KMT2A (0.43) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL679026 | 0.82 | KMT2A (0.64) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL14846370 | 0.81 | CYP19A1 (0.60) | P2RX4CYP19A1KMT2ALMNASRC | |
| SCHEMBL13917819 | 0.81 | KDM4E (0.47) | P2RX4KMT2ALMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053547-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | MERCK PATENT GMBH (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20110068304-A1 | Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof | MERCK PATENT GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-7834136-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2010-11-16 | — | — | US | disclosed |