SCHEMBL679026

SCHEMBL679026

Cc1ccc2c(c1)c1cc(C)ccc1n2Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
LMNA P02545 1/20 0.64
CYP19A1 P11511 1/20 0.60
MIF P14174 3/20 0.56
SRC P12931 1/20 0.56
ALDH1A1 P00352 2/20 0.56
P2RX4 Q99571 2/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
MEN1 O00255 2/20 0.54
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CD74 P04233 1/20 0.53
CACNB4 O00305 1/20 0.49
CACNA1A O00555 1/20 0.49
CACNA1G O43497 1/20 0.49
CACNG3 O60359 1/20 0.49
CACNA1F O60840 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12357944 0.95 CYP19A1 (0.70) KMT2ALMNACYP19A1MIFSRC
SCHEMBL14492826 0.90 P2RX4 (0.56) KMT2ALMNACYP19A1MIFSRC
SCHEMBL13957030 0.89 P2RX4 (0.66) KMT2ALMNACYP19A1ALDH1A1P2RX4
SCHEMBL679980 0.85 CYP19A1 (0.60) KMT2ALMNACYP19A1MIFSRC
SCHEMBL20040416 0.84 MIF (0.53) KMT2ALMNACYP19A1MIFSRC
SCHEMBL20040374 0.84 KMT2A (0.50) KMT2ALMNACYP19A1MIFSRC
SCHEMBL27901716 0.84 KMT2A (0.55) KMT2ALMNAALDH1A1POLBTSHR
SCHEMBL6823481 0.84 KMT2A (0.63) KMT2ALMNACYP19A1MIFSRC
SCHEMBL679037 0.82 P2RX4 (0.50) KMT2ALMNACYP19A1MIFSRC
SCHEMBL6923659 0.82 KMT2A (0.51) KMT2ALMNACYP19A1MIFSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
EP-1932866-B1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GMBH (DE) 2011-07-13 EP disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-20080054794-A1 Organic Electroluminescence Device, Image Display Apparatus and Lighting Apparatus Including the Same, Charge Transport Material and Charge Transport Layer Forming Ink Including the Same Fujiki, Michiya (JP) 2008-03-06 US disclosed