Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 1.00 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988630 | 0.85 | GSK3B (0.74) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL5725649 | 0.82 | GSK3B (0.69) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL10512352 | 0.82 | GSK3B (0.69) | GSK3BDAOMAPTHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7319930 | 0.80 | GSK3B (0.67) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL6802262 | 0.79 | GSK3B (0.65) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL11844863 | 0.78 | DAO (0.71) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL19341288 | 0.76 | GSK3B (0.61) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL15979679 | 0.76 | GSK3B (0.61) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL13563383 | 0.76 | GSK3B (0.60) | GSK3BDAOMAPTHPGDKDM4E | |
| SCHEMBL792551 | 0.76 | DAO (1.00) | GSK3BDAOMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327494-A1 | NON-INVASIVE VENTILATION WITH HIGH FREQUENCY OSCILLATIONS | KONINKLIJKE PHILIPS N.V. (NL) | 2017-11-16 | — | — | US | disclosed |
| WO-2015162269-A1 | MICROBIOCIDAL IMIDAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-29 | — | — | WO | disclosed |
| US-6747057-B2 | SUCH 1-(2-BROMO-4,5-DICHLORO-THIOPHEN-3-YL)-2-CHLORO-ETHANONE FOR TREATMENT OF ALZHEIMER'S DISEASE OR DIABETES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2004-06-08 | — | — | US | disclosed |
| US-20030199508-A1 | Compounds and their therapeutic use | UNIVERSIDAD AUTONOMA DE MADRID (UAM) (ES) | 2003-10-23 | — | — | US | disclosed |
| WO-2003055479-A1 | COMPOUNDS AND THEIR THERAPEUTIC USE RELATED TO THE PHOSPHORYLATING ACTIVITY OF THE ENZYME GSK-3 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199508-A1 | Compounds and their therapeutic use | CNKSR1, CBR1, CBR3 | GSK3B 4/4885DAO 697/4885MAPT 3369/4885 |
| US-20170327494-A1 | NON-INVASIVE VENTILATION WITH HIGH FREQUENCY OSCILLATIONS | CHRM5, CHRNA5, CHRM1 | GSK3B 4578/4885DAO 732/4885MAPT 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.