Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1051113 | 0.85 | TBXAS1 (0.51) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL7279572 | 0.82 | TBXAS1 (0.49) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL4652076 | 0.82 | TBXAS1 (0.49) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| Bicarbonate SCHEMBL29201334 | 0.81 | TBXAS1 (0.51) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP24A1 | |
| SCHEMBL6550536 | 0.80 | TBXAS1 (0.51) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| Acetic Acid SCHEMBL8525552 | 0.79 | TBXAS1 (0.50) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP24A1 | |
| SCHEMBL27909057 | 0.77 | TBXAS1 (0.49) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL12928729 | 0.77 | TBXAS1 (0.51) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 | |
| SCHEMBL7829900 | 0.75 | TBXAS1 (0.46) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP24A1 | |
| SCHEMBL14864939 | 0.75 | TBXAS1 (0.46) | TBXAS1CYP11B1CYP11B2ALDH1A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720856-A1 | DOPAMINE-& X392;-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019112457-A1 | DOPAMINE-Β-HYDROXYLASE INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2019-06-13 | — | — | WO | disclosed |
| WO-2004005407-A2 | TETRA-AZAPENTAMETHINE AND USE THEREOF FOR DYEING KERATINOUS FIBERS | L'OREAL (FR) | 2004-01-15 | — | — | WO | disclosed |