SCHEMBL6790764

SCHEMBL6790764

CC(C)CNS(=O)(=O)c1ccc(N)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
CA1 P00915 11/20 0.61
CA2 P00918 11/20 0.61
CA12 O43570 8/20 0.61
CA9 Q16790 8/20 0.61
CYP3A4 P08684 1/20 0.58
GBA1 P04062 1/20 0.57
CYP2D6 P10635 1/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA5A P35218 1/20 0.51
CA7 P43166 1/20 0.51
CA5B Q9Y2D0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890706 0.95 ALDH1A1 (0.61) ALDH1A1CA1CA2CA12CA9
SCHEMBL11251792 0.91 ALDH1A1 (0.56) ALDH1A1CA1CA2CA12CA9
SCHEMBL6789998 0.86 CA1 (0.57) ALDH1A1CA1CA2CA12CA9
SCHEMBL6789995 0.86 CA1 (0.57) ALDH1A1CA1CA2CA12CA9
SCHEMBL9229800 0.85 ALDH1A1 (0.67) ALDH1A1CA1CA2GBA1GAA
SCHEMBL7862567 0.83 GBA1 (0.74) ALDH1A1CA1CA2CA12CA9
SCHEMBL31234593 0.83 CA1 (0.54) ALDH1A1CA1CA2CA12CA9
SCHEMBL3704958 0.82 CA12 (0.71) ALDH1A1CA1CA2CA12CA9
SCHEMBL20946436 0.82 ALDH1A1 (0.73) ALDH1A1CA1CA2CA12CA9
SCHEMBL2934786 0.81 ALDH1A1 (0.67) ALDH1A1CA1CA2GBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024243485-A1 CDK2 INHIBITORS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2024-11-28 WO disclosed
US-20040110775-A1 Cyclin dependent kinase inhibiting purine derivatives CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2004-06-10 US disclosed
US-6638921-B1 Pharmaceutically acceptable derivatives thereof Cx, R1 and R2 being as defined in the disclosure may be used to inhibit the activity of HIV integrase. PHARMACOR INC. (CA) 2003-10-28 US disclosed
EP-1353922-A1 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES Cancer Research Technology Limited (GB) 2003-10-22 EP disclosed
WO-2003082881-A2 PYRIDOXAL-5-PHOSPHATE DERIVATIVES AS HIV INTEGRASE INHIBITORS PROCYON BIOPHARMA INC. (CA) 2003-10-09 WO disclosed
WO-2002059125-A1 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-08-01 WO disclosed
EP-0644453-A1 Organic nonlinear optical materials HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110775-A1 Cyclin dependent kinase inhibiting purine derivatives CCNA1, CDKL1, CCNK ALDH1A1 2396/4885CA1 2976/4885CA2 2384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.