SCHEMBL6790822

SCHEMBL6790822

CCCCN(CC)c1ccc(F)cc1F

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
CRHR1 P34998 8/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CNR2 P34972 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715939 0.93 CNR2 (0.40) CYP3A4CNR2
SCHEMBL5716023 0.90 CRHR1 (0.39) CYP3A4CRHR1SLC6A2SLC6A4
SCHEMBL6790257 0.89 CYP3A4 (0.42) CYP3A4MAPTMAPK1
SCHEMBL5715845 0.86 SOAT1 (0.39) CNR2
SCHEMBL5716046 0.85 CYP3A4 (0.46) CYP3A4MAPTMAPK1
SCHEMBL5716551 0.82 SOAT1 (0.37) CNR2
SCHEMBL5716516 0.81 CRHR1 (0.32) CYP3A4CRHR1
SCHEMBL5715908 0.80 CYP3A4 (0.43) CYP3A4MAPTMAPK1
SCHEMBL5716042 0.80 CNR2 (0.40) CRHR1CNR2
SCHEMBL5715698 0.79 PSEN1 (0.37) CRHR1LMNAMAPTMAPK1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed