Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.59 |
| ▸ | CALML3 | P27482 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SDHA | P31040 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792072 | 0.87 | MAOA (0.62) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3197840 | 0.86 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14436451 | 0.86 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1383021 | 0.86 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6797249 | 0.85 | MAOA (0.59) | MAOACALML3MAOBLMNAPTGS1 | |
| Hydrochloric Acid SCHEMBL6799766 | 0.85 | MAOA (0.59) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6793136 | 0.85 | MAOA (0.69) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4171562 | 0.85 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL4171585 | 0.85 | MAOA (0.61) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL6799017 | 0.85 | MAOA (0.58) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689779-B2 | PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY | DONG A PHARM. CO., LTD. (KR) | 2004-02-10 | — | — | US | disclosed |