SCHEMBL6791284

SCHEMBL6791284

COC(=O)C=CCc1c(-c2ccc(C(=N)N)cc2)[nH]c2cc(C(=N)N)ccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
KIF11 P52732 1/20 0.37
PLG P00747 3/20 0.37
PLAU P00749 3/20 0.37
F10 P00742 1/20 0.36
PRMT5 O14744 1/20 0.36
PRMT3 O60678 1/20 0.36
CARM1 Q86X55 1/20 0.36
EHMT2 Q96KQ7 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PRMT1 Q99873 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
PRMT7 Q9NVM4 1/20 0.36
KLK6 Q92876 2/20 0.36
KLK8 O60259 1/20 0.36
KLK14 Q9P0G3 1/20 0.36
KLK5 Q9Y337 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6791279 0.99 F2 (0.38) F2KDM4EGAAKIF11PLG
Hydrochloric Acid SCHEMBL6791282 0.99 F2 (0.38) F2KDM4EGAAKIF11PLG
SCHEMBL6789409 0.84 F10 (0.41) F2KDM4EPLGPLAUF10
Hydrochloric Acid SCHEMBL6789400 0.83 F10 (0.40) F2KDM4EPLGPLAUF10
Hydrochloric Acid SCHEMBL6789404 0.83 F10 (0.40) F2KDM4EPLGPLAUF10
SCHEMBL6786964 0.80 KIF11 (0.45) F2KDM4EKIF11PLGPLAU
Hydrochloric Acid SCHEMBL6786963 0.79 KIF11 (0.44) F2KDM4EKIF11PLGPLAU
SCHEMBL6787717 0.78 F2 (0.43) F2PLGPLAUF10PRMT5
SCHEMBL6793787 0.77 F2 (0.40) F2KDM4EGAAF10KLK6
Hydrochloric Acid SCHEMBL6787185 0.77 F2 (0.42) F2PLGPLAUPRMT5PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699862-B1 ANTITUMOR PFIZER INC. 2004-03-02 US claimed