Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889528 | 0.86 | KMT2A (0.64) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL2931917 | 0.77 | KMT2A (0.60) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL2191023 | 0.76 | KMT2A (0.54) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL30619598 | 0.74 | LMNA (0.49) | KMT2AMEN1LMNACA12CA1 | |
| SCHEMBL11584103 | 0.74 | KMT2A (0.56) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL3423468 | 0.74 | KMT2A (0.65) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL3423470 | 0.74 | KMT2A (0.65) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL7249823 | 0.73 | KMT2A (0.59) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL3075872 | 0.72 | KMT2A (0.67) | KMT2AMEN1GSK3AGSK3BMAPT | |
| SCHEMBL28332104 | 0.71 | KMT2A (0.65) | KMT2AMEN1GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197268-A1 | Method of imaging amyloid deposits using substituted rhodanine derivatives | AUGELLI-SZAFRAN CORINNE ELIZAB (US) | 2004-10-07 | — | — | US | disclosed |
| EP-1192144-A1 | RHODANINE DERIVATIVES AND THEIR USE IN INHIBITING AND IMAGING AMYLOIDS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076988-A1 | RHODANINE DERIVATIVES AND THEIR USE IN INHIBITING AND IMAGING AMYLOIDS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040197268-A1 | Method of imaging amyloid deposits using substituted rhodanine derivatives | APP, PSEN1, PSEN2 | KMT2A 4348/4885MEN1 360/4885LMNA 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.