⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866143 | 0.83 | ALOX15 (0.34) | — | |
| SCHEMBL6395180 | 0.81 | — | — | |
| SCHEMBL1116464 | 0.79 | — | — | |
| SCHEMBL28036244 | 0.79 | — | — | |
| SCHEMBL4692524 | 0.77 | CA1 (0.39) | — | |
| SCHEMBL27511801 | 0.77 | ALOX15 (0.33) | — | |
| SCHEMBL27416714 | 0.76 | — | — | |
| SCHEMBL10781106 | 0.76 | ALOX15 (0.36) | — | |
| SCHEMBL27325645 | 0.74 | ALOX15 (0.34) | — | |
| SCHEMBL28122874 | 0.74 | ALOX15 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730683-B2 | Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses | SMITHKLINE BEECHAM CORPORATION | 2004-05-04 | — | — | US | claimed |
| CN-103282034-A | Use of hematopoietic growth factor mimetics | LIGAND PHARM INC | 2013-09-04 | — | — | CN | disclosed |
| CN-103193687-A | Method for preparing sulfonyl chloride in environment-friendly mode | UNIV BEIJING CHEMICAL | 2013-07-10 | — | — | CN | disclosed |
| CN-102656141-A | Hematopoietic growth factor mimetic small molecule compounds and their uses | LIGAND PHARM INC | 2012-09-05 | — | — | CN | disclosed |
| CN-102424665-A | Preparation method of 1-substituted homotaurine | UNIV BEIJING CHEMICAL | 2012-04-25 | — | — | CN | disclosed |
| US-6730683-B2 | Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses | SMITHKLINE BEECHAM CORPORATION | 2004-05-04 | — | — | US | disclosed |
| US-6335340-B1 | REACTING POLYMER BOUND 2-THIOPYRIMIDINE-4-YL IMINE WITH AN ISONITRILE; OXIDATION TO SULFONE OR SULFOXIDE TO RELEASE; AMINATION; ADMINISTERING AS CYTOKINE, INTERLEUKIN, AND TUMOR NECROSIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2002-01-01 | — | — | US | disclosed |