⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296113 | 0.67 | — | — | |
| SCHEMBL519001 | 0.62 | — | — | |
| SCHEMBL3516414 | 0.60 | — | — | |
| SCHEMBL14943979 | 0.60 | — | — | |
| SCHEMBL18647907 | 0.60 | — | — | |
| SCHEMBL7591706 | 0.59 | — | — | |
| SCHEMBL1983124 | 0.55 | — | — | |
| SCHEMBL1028281 | 0.55 | — | — | |
| SCHEMBL1983123 | 0.55 | — | — | |
| SCHEMBL10296597 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | claimed |
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | disclosed |