Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 11/20 | 0.84 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720214 | 0.91 | MAP3K5 (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL3893490 | 0.91 | MAP3K5 (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL3893493 | 0.91 | MAP3K5 (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| Claficapavir SCHEMBL13326245 | 0.91 | HIF1AN (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| Claficapavir SCHEMBL6789043 | 0.91 | HIF1AN (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| Claficapavir SCHEMBL12697026 | 0.91 | HIF1AN (1.00) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL6797191 | 0.90 | MAPT (0.83) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL7641513 | 0.90 | MAPT (0.83) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL3903272 | 0.88 | HIF1AN (0.80) | MAP3K5HIF1ANMEN1PKMKMT2A | |
| SCHEMBL3903277 | 0.88 | HIF1AN (0.80) | MAP3K5HIF1ANMEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198741-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | WYETH | 2004-10-07 | — | — | US | claimed |
| US-20030195213-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | BAILEY THOMAS R (US) | 2003-10-16 | — | — | US | claimed |
| US-20040198741-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | WYETH | 2004-10-07 | — | — | US | disclosed |
| US-20030195213-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | BAILEY THOMAS R (US) | 2003-10-16 | — | — | US | disclosed |
| EP-1128832-A4 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INC (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1128832-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | Viropharma Incorporated (US) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000010573-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES | VIROPHARMA INCORPORATED (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195213-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | RXRG, TREH, RARG | MAP3K5 4055/4885HIF1AN 285/4885MEN1 3202/4885 |
| US-20040198741-A1 | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | RXRG, TREH, RARG | MAP3K5 4055/4885HIF1AN 285/4885MEN1 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.