SCHEMBL6792563

SCHEMBL6792563

CCCCCCN(CC)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.39
MGLL Q99685 1/20 0.37
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
CNR2 P34972 2/20 0.35
KCNH2 Q12809 6/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5082545 0.91 DNM1 (0.42) DNM1MGLLCNR2KCNH2TSHR
SCHEMBL29002046 0.91 DNM1 (0.42) DNM1MGLLCNR2KCNH2TSHR
SCHEMBL3978473 0.91 DNM1 (0.42) DNM1MGLLCNR2KCNH2TSHR
SCHEMBL5088802 0.91 DNM1 (0.42) DNM1MGLLCNR2KCNH2TSHR
SCHEMBL21519592 0.91 DNM1 (0.42) DNM1MGLLCNR2KCNH2TSHR
Hydrochloric Acid SCHEMBL29002048 0.89 DNM1 (0.44) DNM1MGLLKCNH2TSHRTHRB
SCHEMBL5716608 0.89 DNM1 (0.41) DNM1MGLLCYP3A4MAPTMAPK1
SCHEMBL5716286 0.88 DNM1 (0.39) DNM1MGLLCYP3A4MAPK1KCNH2
SCHEMBL5715545 0.88 DNM1 (0.39) DNM1MGLLCYP3A4MAPK1KCNH2
SCHEMBL5715858 0.86 DNM1 (0.38) DNM1MGLLTSHRTHRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed