Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376751 | 0.90 | ADORA1 (0.46) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29372375 | 0.90 | ADORA1 (0.46) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6223187 | 0.89 | ADORA1 (0.45) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6220853 | 0.87 | KDM4E (0.46) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27453761 | 0.87 | KDM4E (0.47) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6222539 | 0.87 | ADORA1 (0.44) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6220910 | 0.86 | KDM4E (0.44) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6223514 | 0.86 | KDM4E (0.45) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6221158 | 0.86 | ADORA1 (0.49) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6224664 | 0.85 | KDM4E (0.43) | ADORA1KDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740662-B1 | HAVING 2-OXO-1,2-DIHYDRO- FUNCTIONALITY; PHOSPHODIESTERASE INHIBITORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-25 | — | — | US | disclosed |