SCHEMBL6792995

SCHEMBL6792995

CN(c1ccccc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HTT P42858 1/20 0.37
NR1H3 Q13133 7/20 0.37
NR1H2 P55055 5/20 0.36
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
KCNN4 O15554 1/20 0.33
POLQ O75417 1/20 0.33
TACR1 P25103 1/20 0.33
FAAH O00519 1/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715796 0.84 MEN1 (0.41) MEN1KMT2AHTTNR1H3NR1H2
SCHEMBL11248967 0.79 NPC1 (0.42) MEN1KMT2ANR1H3NR1H2ALDH1A1
SCHEMBL11247704 0.79 NPC1 (0.42) MEN1KMT2ANR1H3NR1H2ALDH1A1
SCHEMBL28357481 0.77 MEN1 (0.39) MEN1KMT2AHTTNR1H3NR1H2
SCHEMBL4033878 0.77 MEN1 (0.42) MEN1KMT2AHTTNR1H3NR1H2
SCHEMBL6791746 0.76 TSHR (0.40) NR1H3NR1H2ALDH1A1TSHR
SCHEMBL11317352 0.76 CYP2A6 (0.48) ALDH1A1
SCHEMBL6790778 0.75 NR1H2 (0.32) NR1H3NR1H2ALDH1A1CA1CA2
SCHEMBL6789899 0.74 TP53 (0.34) MEN1KMT2ANR1H3NR1H2ALDH1A1
SCHEMBL6738356 0.73 KCNN4 (0.41) MEN1KMT2AHTTNR1H3NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed