SCHEMBL6793207

SCHEMBL6793207

CC(=O)NC[C@H]1CN(c2ccc(-c3ccc(-n4cnnn4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.60
MAOB P27338 3/20 0.53
CALML3 P27482 3/20 0.53
LMNA P02545 1/20 0.53
PTGS1 P23219 1/20 0.53
SDHA P31040 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22352843 0.93 MAOA (0.51) MAOAMAOBCALML3
SCHEMBL22352842 0.93 MAOA (0.51) MAOAMAOBCALML3
SCHEMBL5805368 0.91 MAOA (0.59) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5804985 0.91 MAOA (0.51) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5804803 0.91 MAOA (0.62) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL6793468 0.89 MAOA (0.62) MAOA
SCHEMBL22352821 0.88 MAOA (0.51) MAOAMAOBCALML3
SCHEMBL22352820 0.88 MAOA (0.51) MAOAMAOBCALML3
SCHEMBL5805999 0.88 MAOA (0.60) MAOAMAOBCALML3LMNAPTGS1
SCHEMBL5809660 0.88 MAOA (0.61) MAOAMAOBCALML3LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof DONG A PHARM. CO., LTD. (KR) 2003-09-04 US claimed
US-6689779-B2 PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY DONG A PHARM. CO., LTD. (KR) 2004-02-10 US disclosed
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof DONG A PHARM. CO., LTD. (KR) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof OXA1L, ODC1, PDCD4 MAOA 763/4885MAOB 593/4885CALML3 4610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.