SCHEMBL6793363

SCHEMBL6793363

CC1(c2ccccc2)SC(=S)N(Nc2ccccc2)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
MAPT P10636 12/20 0.40
ALDH1A1 P00352 10/20 0.40
KMT2A Q03164 7/20 0.40
TDP1 Q9NUW8 6/20 0.40
GAA P10253 5/20 0.40
MEN1 O00255 5/20 0.40
L3MBTL1 Q9Y468 4/20 0.40
MAPK1 P28482 3/20 0.40
KDM4E B2RXH2 2/20 0.39
HTT P42858 4/20 0.37
NPSR1 Q6W5P4 3/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
RECQL P46063 2/20 0.36
JAK2 O60674 1/20 0.36
NSD2 O96028 1/20 0.36
NPY2R P49146 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6791629 0.84 MAPT (0.36) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6788230 0.80 CYP1A2 (0.37) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6788228 0.80 CYP1A2 (0.37) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6792644 0.80 MAPT (0.32) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6792650 0.80 MAPT (0.32) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6790159 0.78 CYP1A2 (0.36) CYP1A2MAPTALDH1A1TDP1GAA
SCHEMBL6790155 0.78 CYP1A2 (0.36) CYP1A2MAPTALDH1A1TDP1GAA
SCHEMBL6791051 0.74 MGAM (0.40) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL6791047 0.74 MGAM (0.40) CYP1A2MAPTALDH1A1KMT2ATDP1
SCHEMBL10881711 0.74 ALDH1A1 (0.34) CYP1A2ALDH1A1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6713629-B2 PLANT FUNGICIDE NIPPON SODA CO., LTD. (JP) 2004-03-30 US disclosed
US-20030114649-A1 5,5-Disubstituted thiazolidine derivative pesticides NIPPON SODA CO., LTD. 2003-06-19 US disclosed
US-6476055-B1 5,5-disubstituted thiazolidine derivative pesticides NIPPON SODA CO. LTD. (JP) 2002-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114649-A1 5,5-Disubstituted thiazolidine derivative pesticides NAT1, DDT, TH CYP1A2 37/4885MAPT 4764/4885ALDH1A1 599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.