SCHEMBL679366

SCHEMBL679366

CC(=O)C(=O)OC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 2/20 0.50
CYP1A2 P05177 2/20 0.50
GSR P00390 2/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
GRIA4 P48058 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIK2 Q13002 1/20 0.50
GRIK3 Q13003 1/20 0.50
GRIN2B Q13224 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9755475 1.00 SLC1A1 (0.50) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL7158243 0.88 GSR (0.58) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL28385659 0.86 GSR (0.56) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL28296238 0.86 GSR (0.56) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL28980806 0.86 GSR (0.56) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL9193738 0.85 SLC1A1 (0.34) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL2803038 0.85 SLC1A1 (0.54) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL28241081 0.84 SLC1A1 (0.33) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL3715039 0.84 SLC1A1 (0.48) SLC1A1CYP1A2GSRGRM8GRM6
SCHEMBL4406473 0.83 KMT2A (0.55) SLC1A1CYP1A2GSRGRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118121582-A Medicine for reducing triptolide induced hepatotoxicity 西南大学 2024-06-04 CN claimed
CN-117079743-A Statin drug treatment effect prediction model and application 中日友好医院(中日友好临床医学研究所) 2023-11-17 CN claimed
CN-116042496-A Escherichia coli genetically engineered bacterium for producing L-citrulline through fermentation, construction method and application 河南巨龙生物工程股份有限公司 2023-05-02 CN claimed
EP-2260100-B1 tPA MUTANT IN THE TREATMENT OF ACUTE BRAIN INJURY AND NEURODEGENERATIVE DISORDERS HADASIT MED RES SERVICE (IL) 2015-06-10 EP claimed
CN-102574791-A Enzymatic transamination of cyclopamine analogs INFINITY PHARMACEUTICALS INC 2012-07-11 CN claimed
CN-101040983-A Zizhen pills for protecting liver ZHANG KEHUAI (CN) 2007-09-26 CN claimed
EP-0034213-B1 A STABILIZED AQUEOUS COENZYME SOLUTION FOR USE IN A CLINICAL ASSAY, A METHOD OF STABILIZING A LABILE COENZYME IN AN AQUEOUS CLINICAL ASSAY SOLUTION AND A KIT FOR USE IN SAID CLINICAL ASSAY Modrovich, Ivan Endre (US) 1984-11-07 EP claimed
JP-58135000-A None JP disclosed
JP-60060550-A None JP disclosed
EP-4397678-A2 METHODS AND COMPOSITIONS FOR TREATING LIVER DISEASE The United States Government as Represented by the Department of Veterans Affairs (US) 2024-07-10 EP disclosed
WO-2024123839-A1 COMPOSITIONS, MODIFICATIONS, PROPERTIES, AND METHODS FOR DELIVERY OF GENETIC CARGO TO CELLS NANOTRANSFER CORPORATION (US) 2024-06-13 WO disclosed
WO-2024073074-A1 BIOLOGICAL INDICATOR WITH ENHANCED VOLATILE ORGANIC COMPOUND DETECTION O&M HALYARD, INC. (US) 2024-04-04 WO disclosed
CN-117750958-A Methods of treating interstitial cystitis/bladder pain syndrome 普渡制药公司 2024-03-22 CN disclosed
JP-S58135000-A METHOD AND APPARATUS FOR DETERMINATION OF GLUTAMIC ACID OXALOACETIC ACID TRANSAMINASE AND GLUTAMIC ACID PYRUVIC ACID TRANSAMINASE YOKOGAWA HOKUSHIN ELECTRIC CORP 1983-08-11 JP disclosed
EP-0071640-A4 NON-A, NON-B HEPATITIS VIRUS. CONNAUGHT LAB (US) 1983-05-16 EP disclosed
EP-0071640-A1 NON-A, NON-B HEPATITIS VIRUS. CONNAUGHT LAB (US) 1983-02-16 EP disclosed
EP-0058676-A4 NON-A, NON-B HEPATITIS ASSAY AND VACCINE. CONNAUGHT LAB (CA) 1982-11-25 EP disclosed
EP-0058676-A1 NON-A, NON-B HEPATITIS ASSAY AND VACCINE. CONNAUGHT LAB (CA) 1982-09-01 EP disclosed
WO-1982002774-A1 NON-A,NON-B HEPATITIS VIRUS BAXTER TRAVENOL LAB (US) 1982-08-19 WO disclosed
WO-1982000205-A1 NON-A,NON-B HEPATITIS ASSAY AND VACCINE BAXTER TRAVENOL LAB (US) 1982-01-21 WO disclosed