SCHEMBL4406473

SCHEMBL4406473

NC(=O)C(=O)OC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
ALOX15 P16050 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
SLC1A1 P43005 2/20 0.52
GSR P00390 2/20 0.52
CYP1A2 P05177 2/20 0.52
GRM8 O00222 2/20 0.52
GRM6 O15303 2/20 0.52
GRM7 Q14831 2/20 0.52
GRM4 Q14833 2/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7158243 0.90 GSR (0.58) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28385659 0.88 GSR (0.56) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28980806 0.88 GSR (0.56) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28296238 0.88 GSR (0.56) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL27856610 0.85 SLC1A1 (0.52) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28394544 0.85 SLC1A1 (0.52) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL8652131 0.84 KMT2A (0.59) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL8648790 0.84 KMT2A (0.59) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28015254 0.84 SLC1A1 (0.60) KMT2AALOX15BLMPMP22SLC1A1
SCHEMBL28203156 0.84 SLC1A1 (0.60) KMT2AALOX15BLMPMP22SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916765-A Composition for preventing, improving or treating diseases caused by protein nitrification comprising peptide having tyrosine at its end as active ingredient 庆尚国立大学校 产学协力团 2023-10-20 CN disclosed
CN-115996645-A Composition for preventing, improving or treating diseases caused by nitration of tyrosine in protein comprising tyrosine as active ingredient 庆尚国立大学校 产学协力团 2023-04-21 CN disclosed
CN-108473944-A Novel Lactobacillus having various functions and use thereof 庆熙大学校产学协力团 2018-08-31 CN disclosed
US-20180002171-A1 NANO-BIOREACTOR APPARATUS AND METHOD OF MANIPULATING EXTRACELLULAR METABOLIC SYSTEMS AMOABEDINY GHASSEM (IR) 2018-01-04 US disclosed
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2009-08-20 US disclosed
EP-1965778-A2 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NewThera (FR) 2008-09-10 EP disclosed
WO-2007017768-A2 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2007-02-15 WO disclosed
EP-1752143-A1 Novel uses for drugs targeting glutamine synthetase NewThera (FR) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE GLUL, GLS2, ASNS KMT2A 3171/4885ALOX15 1435/4885BLM 4619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.