Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 19/20 | 0.83 |
| ▸ | GRM3 | Q14832 | 19/20 | 0.83 |
| ▸ | GRM6 | O15303 | 3/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.58 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6908223 | 0.84 | GRM2 (0.80) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6908226 | 0.84 | GRM2 (0.80) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6791452 | 0.83 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6795226 | 0.82 | GRM2 (0.76) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6789006 | 0.82 | GRM2 (0.74) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6789996 | 0.82 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6908309 | 0.82 | GRM2 (0.77) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6908314 | 0.82 | GRM2 (0.77) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6792051 | 0.81 | GRM2 (0.67) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6794790 | 0.80 | GRM2 (1.00) | GRM2GRM3GRM6GRM4GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |