Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.41 |
| ▸ | EP300 | Q09472 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP7 | P09237 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783525 | 0.87 | ACACB (0.58) | GRIA1GRIA2GRIA3GRIA4ACACB | |
| SCHEMBL6787433 | 0.83 | GRIA4 (0.61) | GRIA1GRIA2GRIA3GRIA4ACACB | |
| SCHEMBL6783646 | 0.79 | GRIA2 (0.50) | GRIA1GRIA2GRIA3GRIA4MMP2 | |
| SCHEMBL6789706 | 0.79 | GRIA4 (0.56) | GRIA4ACACBMMP2CTSLCTSB | |
| SCHEMBL6787512 | 0.78 | ACACB (0.44) | ACACB | |
| SCHEMBL21274670 | 0.78 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4ACACB | |
| SCHEMBL9435111 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4MMP2 | |
| SCHEMBL6783173 | 0.71 | GRIA1 (0.50) | GRIA1GRIA2GRIA3GRIA4MMP2 | |
| SCHEMBL28508296 | 0.71 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4ACACB | |
| SCHEMBL2134262 | 0.70 | GRIA4 (1.00) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | ARNOLD MACKLIN BRIAN (US) | 2004-05-20 | — | — | US | disclosed |
| US-6617351-B1 | Amide, carbamate, and urea derivatives | ELI LILLY AND COMPANY | 2003-09-09 | — | — | US | disclosed |
| EP-0976744-A1 | Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097499-A1 | Amide, carbamate, and urea derivatives | GRIN2A, GLUL, GRIK5 | GRIA1 30/4885GRIA2 25/4885GRIA3 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.