Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 14/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796561 | 0.93 | ESR1 (0.51) | ESR1EDNRBEDNRAESR2MLNR | |
| SCHEMBL4144091 | 0.92 | ESR1 (0.51) | ESR1ALOX5AP | |
| SCHEMBL6802235 | 0.92 | ESR1 (0.52) | ESR1GPR34EDNRBEDNRAESR2 | |
| SCHEMBL6794385 | 0.91 | ESR1 (0.53) | ESR1EDNRBEDNRAESR2MLNR | |
| SCHEMBL6789437 | 0.90 | ESR1 (0.54) | ESR1EDNRBEDNRAESR2PLA2G2A | |
| SCHEMBL4151712 | 0.88 | ESR1 (0.51) | ESR1EDNRBEDNRAESR2MLNR | |
| SCHEMBL635012 | 0.88 | PLA2G2A (0.56) | ESR1EDNRBEDNRAESR2MLNR | |
| SCHEMBL6796210 | 0.88 | ESR1 (0.47) | ESR1EDNRBEDNRAESR2MLNR | |
| SCHEMBL19949697 | 0.87 | ESR1 (0.60) | ESR1ESR2MLNRABCB11NR3C1 | |
| SCHEMBL4152278 | 0.87 | EDNRB (0.52) | ESR1EDNRBEDNRAPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229932-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indoles as estrogenic agents | WYETH | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229932-A1 | 2-Phenyl-1-[4-(2-Aminoethoxy)-Benzyl]-Indoles as estrogenic agents | ESR2, ESR1, GPER1 | ESR1 2/4885ALOX5AP 765/4885GPR34 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.