Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844009 | 0.93 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL6793450 | 0.93 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL6799331 | 0.92 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL6801679 | 0.91 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL6804329 | 0.90 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5844156 | 0.89 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL6393420 | 0.88 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL6796398 | 0.87 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5844732 | 0.87 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL5845326 | 0.87 | CRHR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833378-B2 | Pyridines, pyrimidines, purinones, pyrrolopyrimidinones and pyrrolopyridinones; useful in the treatment disorders including CNS and stress-related disorders. | PFIZER INC | 2004-12-21 | — | — | US | disclosed |