Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.77 |
| ▸ | CA2 | P00918 | 13/20 | 0.77 |
| ▸ | CA7 | P43166 | 13/20 | 0.77 |
| ▸ | CA9 | Q16790 | 13/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | CASP1 | P29466 | 1/20 | 0.77 |
| ▸ | BACE1 | P56817 | 1/20 | 0.77 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.77 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL3930226 | 0.88 | CA1 (0.90) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL29350272 | 0.88 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL17986 | 0.88 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL3658029 | 0.88 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| Butyl Alcohol SCHEMBL28576380 | 0.86 | CA1 (0.63) | CA1CA2CA7CA9ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL1286269 | 0.85 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 | |
| Water SCHEMBL592691 | 0.85 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28516500 | 0.85 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL29080606 | 0.85 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL4921601 | 0.85 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113514597-B | Thin-layer chromatography identification method of gastrodia tuber dizziness relieving granule | 鲁南厚普制药有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117942380-A | A Chinese medicinal composition for treating diabetic nephropathy and its quality detection method | 江苏省中医院 | 2024-04-30 | — | — | CN | claimed |
| CN-117723653-A | Thin-layer identification method of Xuanqi Tongbi capsules | 南京中山制药有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-114262370-B | Sea anemone polypeptide toxin Hc-GQ and preparation method and application thereof | 海南医学院 | 2023-07-14 | — | — | CN | claimed |
| CN-115902084-A | Method for detecting quality of spleen-tonifying miscarriage-prevention granules | 杭州市中医院 | 2023-04-04 | — | — | CN | claimed |
| CN-112666281-B | Production method of lung clearing and toxin expelling soup established based on fingerprint model | 广东志道医药科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-115112797-A | Method for detecting quality of children's granule for removing food retention and relieving cough and application thereof | 鲁南厚普制药有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-115060713-A | Preparation method of molecularly imprinted paper-based microfluidic chip based on metal organic framework | 杭州智泓达科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-112707852-B | Combined preparation method of garlic extract | 青岛博恩高科生物技术有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-112834684-B | Production method of lung-clearing and toxin-expelling soup established based on thin-layer identification method | 广东志道医药科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-109061030-B | Quality detection method of antitoxic leukogenic mixture | 广西壮族自治区药用植物园 | 2020-09-15 | — | — | CN | claimed |
| CN-111467443-A | Preparation and quality control method of traditional Chinese medicine composition for preventing and treating asthma in remission stage | 延边大学 | 2020-07-31 | — | — | CN | claimed |
| CN-107474118-B | Homo-cyclic peptide Cyclo- (Cys)6Preparation method of (1) | 中国工程物理研究院核物理与化学研究所 | 2020-07-28 | — | — | CN | claimed |
| CN-107400162-B | Homocyclic peptide Cyclo- [ (Asn)5-Cys]Preparation method of (1) | 中国工程物理研究院核物理与化学研究所 | 2020-07-21 | — | — | CN | claimed |
| CN-107400161-B | Preparation method of homocyclic peptide Cyclo- [ (Asp)5-Gly ] | 中国工程物理研究院核物理与化学研究所 | 2020-07-21 | — | — | CN | claimed |
| CN-111239127-A | Simple evaluation method for umami intensity of compound umami seasoning | 漯河医学高等专科学校 | 2020-06-05 | — | — | CN | claimed |
| CN-110967305-A | Test paper box for rapidly detecting compost maturity and using method thereof | 重庆工商大学 | 2020-04-07 | — | — | CN | claimed |
| CN-110907562-A | Quality detection method of stomach harmonizing and detoxifying capsules | 湖南新汇制药股份有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-108315308-A | A kind of biologically active COX18 polypeptides and its synthetic method and purposes | 中南民族大学 | 2018-07-24 | — | — | CN | claimed |
| CN-106929488-A | A kind of COX with bioactivity52‑69Solid phase synthesis process of polypeptide and application thereof | 中南民族大学 | 2017-07-07 | — | — | CN | claimed |