Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12316779 | 0.88 | MEN1 (0.85) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL13726123 | 0.87 | MEN1 (0.74) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL13726528 | 0.85 | MEN1 (0.72) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL22810443 | 0.85 | KMT2A (0.71) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL13726176 | 0.83 | LMNA (0.75) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL30847026 | 0.83 | LMNA (0.75) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL11928962 | 0.81 | CHRM2 (0.72) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL13727299 | 0.81 | LMNA (1.00) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL13727123 | 0.81 | MAPT (0.80) | MEN1KMT2ATSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30087523 | 0.80 | APOBEC3A (0.73) | MEN1KMT2ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821964-B2 | FOR PROPHYLAXIS AND THERAPY OF DISEASES ASSOCIATED WITH MONOCYTE ACCUMULATION, LYMPHOCYTE ACCUMULATION OR LEUCOCYTE ACCUMULATION | PFIZER INC | 2004-11-23 | — | — | US | disclosed |